Drugs & Vitamins

Zinecard Active Ingredients: Dexrazoxane Injection Representative Names: Zinecard What is dexrazoxane injection? What should I tell my health care provider before I take this medicine? How should I use this medicine? What if I miss a dose? What drug(s) may interact with dexrazoxane? What side effects may I notice from receiving dexrazoxane? What should I watch for while taking dexrazoxane? Where can I keep my medicine? What is dexrazoxane injection? (Back to top) DEXRAZOXANE is used to protect against damage caused by certain chemotherapy. It can help stop heart damage in specific patients if given with doxorubicin. It also helps to reduce damage if certain chemotherapy agents accidentally leak from a vein and into other areas of the body. What should I tell my health care provider before I take this medicine? (Back to top) They need to know if you have any of these conditions: •heart disease •renal disease •previous chemotherapy or radiation therapy •an unusual or allergic reaction to dexrazoxane, other medicines, foods, dyes, or preservatives •pregnant or trying to get pregnant •breast-feeding How should I use this medicine? (Back to top) Dexrazoxane is for injection or infusion into a vein. It is given by a health-care professional in a hospital or clinic setting prior to receiving chemotherapy. Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed. What if I miss a dose? (Back to top) This does not apply. What drug(s) may interact with dexrazoxane? (Back to top) No interactions between dexrazoxane and other medicines have been reported. Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines. What side effects may I notice from receiving dexrazoxane? (Back to top) Side effects are caused not only by dexrazoxane, but by the chemotherapy or other medicines taken. Side effects that you should report to your prescriber or health care professional as soon as possible: •fever, chills, or sore throat •mouth sores •unusual bleeding or bruising •unusual tiredness, or weakness •pain at the injection site •vomiting Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome): •confusion •depression •diarrhea •hair loss •nausea What should I watch for while taking dexrazoxane? (Back to top) This medicine may make you feel generally unwell. Report any side effects as above, but continue your course of medicine even though you feel ill, unless your prescriber or health care professional tells you to stop. The chemotherapy can cause blood problems. This can mean slow healing and a risk of infection. Try to avoid cutting or injuring yourself. Problems can arise if you need dental work, and in the day to day care of your teeth. Try to avoid damage to your teeth and gums when you brush or floss your teeth. While you are receiving this medicine you will be more susceptible to infection. Try to avoid people with colds, flu, and bronchitis. Do not have any vaccinations without your prescriber's approval and avoid anyone who has recently had oral polio vaccine. Call your prescriber or health care professional for advice if you get a fever, chills or sore throat. Do not treat yourself. Where can I keep my medicine? (Back to top) Keep out of the reach of children. Dexrazoxane is only given in a hospital or clinic setting prior to chemotherapy; you will not take this medicine at home. Last Updated:09/14/2007 CLINICAL PHARMACOLOGY© GOLD STANDARD MULTIMEDIA INC, ALL RIGHTS RESERVED

Note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It should not be construed to indicate that the use of the product is safe, appropriate, or effective for you. Consult your healthcare professional before taking the product.